Trained killer Ladybug wants to give up the life but is pulled back in by his handler Maria Beetle in order to collect a briefcase on a bullet train heading from Tokyo to Morioka. On board are fellow assasins Kimura, the Prince, Tangerine, and Lemon. Once on board the five assasins discover that their objectives are all connected.

Follows a young social worker who must stop a supernatural entity that is tormenting the family that she was investigating in order to save the parents from losing the custody of their child.